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If you are one of millions of Americans who live with major depression, bipolar disorder or schizophrenia, atypical antipsychotic drugs like Abilify can make a difference in your quality of life. Mental illnesses can cripple, and doctors prescribe these drugs to manage symptoms and help people live more normal lives. The Otsuka Phamaceutical Co. developed Abilify (aripiprazole), and the U.S. Food and Drug Administration (FDA) first approved it in 2002 as a treatment for schizophrenia. Otsuka partnered with Bristol-Myers Squibb to market it.

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However, the number of people diagnosed with schizophrenia is small, so to make the antipsychotic drug more profitable, Otsuka and Bristol-Myers asked the FDA to approve Abilify for more uses. It is most often marketed today as a combination medication with other prescription drugs to treat major depression, although it also has many other approved uses.

After its initial approval, the FDA expanded Abilify to treat:

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